Abstract: Suture Materials Containing the Antimicrobial Taurolidine
نویسندگان
چکیده
Suday, Sptem er 5, 2016 grant R01 GM087609 (to Dr. H. Peter Lorenz), a gift from Ingrid Lai and Bill Shu in honor of Anthony Shu (to Dr. H. Peter Lorenz), Hagey Laboratory for Pediatric Regenerative Medicine and The Oak Foundation (to Drs. Geoffrey C. Gurtner, H. Peter Lorenz, and Michael T. Longaker), Gunn/Olivier fund (to Drs. Irving L. Weissman and Michael T. Longaker), and NIH grant U01 HL099776 (to Dr. Michael T. Longaker). None of the authors has a financial interest in any of the products, devices, or drugs mentioned in this manuscript.
منابع مشابه
Antimicrobial activity of a novel catheter lock solution.
Intravascular catheter-associated bloodstream infections significantly increase rates of morbidity and hospital costs. Microbial colonization and development of biofilms, which are known to be recalcitrant to antibiotic therapy, often lead to the loss of otherwise patent vascular access systems. We evaluated a new taurolidine- and citrate-based catheter lock solution (Neutrolin; Biolink Corpora...
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In vitro, the antimicrobial agent taurolidine inhibited virtually all of the bacteria tested, including vancomycin-resistant enterococci, oxacillin-resistant staphylococci, and Stenotrophomonas maltophilia, at concentrations between 250 and 2,000 microg/ml. Taurolidine was not effective in experimental endocarditis. While it appears unlikely that this antimicrobial would be useful for systemic ...
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Biricik H.S., M. Cabalar, M.Y. Gulbahar: Oral Papillomatosis in a Dog and its Therapy with Taurolidine. Acta Vet. Brno 2008, 77: 373-375. The efficacy of taurolidine on the treatment of oral papillomatosis in a 1-year-old Turkish Kangal dog was evaluated. Diagnosis of the papillomatosis was based on clinical signs, histopathological and immunohistochemical examinations. The dog received 45 mg/k...
متن کاملComparison of ML8-X10 (a prototype oil-in-water micro-emulsion based on a novel free fatty acid), taurolidine/citrate/heparin and vancomycin/heparin antimicrobial lock solutions in the eradication of biofilm-producing staphylococci from central venous catheters.
OBJECTIVES Antimicrobial lock solutions are used for prevention and management of catheter-related bloodstream infections. ML8-X10 (a prototype oil-in-water micro-emulsion based on a novel free fatty acid), vancomycin/heparin and taurolidine/citrate/heparin (Taurolock™-Hep500) lock solutions were tested against biofilm-forming Staphylococcus epidermidis and methicillin-susceptible Staphylococcu...
متن کاملTaurolidine lock: the key to prevention of recurrent catheter-related bloodstream infections.
The literature shows that repeated courses of antibiotics and catheter removals in a subset of patients suffering from multiple catheter-related bloodstream infections (CRBSI), are unlikely to prevent recurrence. In acceding to preventative strategies, we report our application of the antimicrobial chemotherapeutic Taurolidine used as a daily flush solution in seven home TPN patients suffering ...
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